Table 2.
Patient | AUC (nM.Peptide) |
---|---|
2 | 0.0361*106 |
4 | 0.1191*106 |
16 | 0.0417*106 |
23 | 0.1906*106 |
3 | 2.5802*106 |
5 | 0.4751*106 |
7 | 2.2249*106 |
8 | 1.9886*106 |
10 | 0.3754*106 |
All the peptides with an SMM-IC50 of <100 nM were plotted in order of ascending IC50, and the area under the curve for the resulting graph for each patient was determined (Formula 1). This value represents a summary measure of the number of peptides with a high binding affinity and their binding affinities in each DRP and is described by the dimensionless unit, nM.Peptide. See Figure 4 for the individual plots. Unrelated DRP are shaded gray.