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. 2014 Nov 6;5:529. doi: 10.3389/fimmu.2014.00529

Table 2.

HLA-specific alloreactivity potential.

Patient AUC (nM.Peptide)
 2 0.0361*106
 4 0.1191*106
16 0.0417*106
23 0.1906*106
 3 2.5802*106
 5 0.4751*106
 7 2.2249*106
 8 1.9886*106
 10 0.3754*106

All the peptides with an SMM-IC50 of <100 nM were plotted in order of ascending IC50, and the area under the curve for the resulting graph for each patient was determined (Formula 1). This value represents a summary measure of the number of peptides with a high binding affinity and their binding affinities in each DRP and is described by the dimensionless unit, nM.Peptide. See Figure 4 for the individual plots. Unrelated DRP are shaded gray.