Table 1.
Comparisons of interest (M denotes main comparisons of interest, s denotes secondary comparisons of interest)
| Outcome reference number | Outcome | Bl vs. Sh | Ext vs.-A | Sl vs. Dble | Cl vs. N-Cl | Cat vs. P910 |
|---|---|---|---|---|---|---|
|
Women’s health and mortality
| ||||||
| 1 i) |
Pelvic pain |
s |
s |
s |
M |
s |
| ii) |
Dysmenorrhoea |
s |
s |
s |
s |
s |
| iii) |
Deep dyspareunia |
s |
s |
s |
M |
s |
| iv) |
Urinary symptoms |
s |
s |
s |
s |
s |
| 2 |
Diagnostic laparoscopy or diagnostic laparotomy - not related to pregnancy |
s |
s |
s |
M |
s |
| 3 |
Hysterectomy or tubal/ovarian surgery - not related to pregnancy |
s |
s |
s |
M |
s |
| 4 |
Bladder or bowel damage – not related to pregnancy |
s |
s |
s |
M |
s |
| 5 i) |
Abdominal hernias |
M |
|
|
s |
|
| ii) |
Bowel obstruction |
s |
s |
s |
M |
s |
| 6 |
Woman’s death |
|
s |
M |
s |
M |
|
Reproductive status
|
|
|
|
|
|
|
| 7 i) |
Women with no subsequent pregnancy – voluntary |
s |
|
|
s |
|
| ii) |
Women with no subsequent pregnancy – involuntary |
s |
M |
s |
M |
s |
| 8 |
Fertility treatments |
s |
M |
s |
M |
s |
|
Subsequent pregnancies
| ||||||
| 9 |
Any subsequent pregnancy |
s |
s |
s |
s |
s |
| i) |
Interpregnancy interval |
s |
s |
s |
s |
s |
| ii) |
Miscarriage |
|
s |
s |
|
s |
| iii) |
Ectopic pregnancy |
|
M |
s |
M |
s |
| iv) |
Gestation |
|
s |
s |
|
s |
| v) |
Stillbirth |
|
s |
M |
|
M |
| vi) |
Neonatal death |
|
s |
M |
|
M |
| vii) |
Mode of delivery |
|
s |
M |
|
M |
| viii) |
Other pregnancy complications (composite of a-i) |
|
s |
M |
|
M |
| a |
Uterine rupture |
|
s |
M |
|
M |
| b |
Uterine scar dehiscence |
|
s |
M |
|
M |
| c |
Placenta praevia |
|
s |
M |
|
M |
| d |
Morbidly adherent placenta |
|
s |
M |
|
M |
| e |
Abruption |
|
s |
M |
|
M |
| f |
Postpartum haemorrhage requiring transfusion of >1 unit of whole blood or packed cells |
|
s |
M |
|
M |
| g |
Severe infection within 6 weeks postpartum |
|
s |
M |
|
M |
| h |
Hysterectomy up to 6 weeks postpartum |
|
s |
M |
|
M |
| i |
Manual removal of placenta |
|
s |
M |
|
M |
| ix) |
Bladder or bowel damage –at the time of subsequent Caesarean section |
s |
s |
s |
s |
s |
|
CORONIS children – morbidity and mortality
| ||||||
| 10 | Death or serious morbidity of CORONIS child | M | ||||
Key: Bl vs. Sh = Blunt versus sharp abdominal entry, Ext vs. I-A = Exteriorisation of the uterus for repair versus intra-abdominal repair, Sl vs. Dble = Single versus double layer closure of the uterus, Cl vs. N-Cl = Closure versus non-closure of the peritoneum (pelvic and parietal), Cat vs. P910 = Chromic catgut versus Polyglactin-910 for uterine repair.