Table 2.
power to detect a specified difference for a fixed sample size
| Outcome examples | Event rate in 1st group e.g. single layer closure | Event rate in 2nd group e.g. double layer closure | Absolute risk difference | Power available to detect this difference |
|---|---|---|---|---|
|
For all women (number estimated to be ~7,400) | ||||
| Involuntary infertility |
3% |
4.5% |
1.5% |
92% |
| Subsequent pregnancy |
48% |
44% |
4% |
93% |
| Dyspareunia |
19% |
16% |
3% |
92% |
|
For women who have a subsequent pregnancy (number estimated to be ~5,900) | ||||
| Uterine rupture or dehiscence |
4% |
5.9% |
1.9% |
92% |
| Preterm birth | 10% | 7.5% | 2.5% | 93% |