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In vitro effects of human DBH promoter variant C-2734T (rs1076150): Balanced mutants on two haplotype backgrounds (HAP2, HAP4) yield consistent (C > T) effects on transcription in chromaffin cells. Strength of the promoter variants is shown as luciferase activity in PC12 cell type (mean ± SEM). P-values are result of C versus T variant comparison for each haplotype background by ANOVA.
