Figure 3.
In vivo effects of DBH promoter functional variants T-2734C (rs1076150), C-2073T (rs1989787) and C-970T (rs1611115) on plasma DBH activity (IU/l). (A) DBH promoter diploid haplotype (rs1076150 → rs1989787 → rs1611115) effect on pDBH activity (IU/l). Only subjects homozygous for a given haplotype (rs1076150 → rs1989787 → rs1611115) are shown. (B) Effect of DBH promoter haplotype (rs1076150 → rs1989787 → rs1611115) copy number (0, 1, or 2 copies per genome) on pDBH activity (IU/l, adjusted mean ± SEM).
