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Abnormal disulfide-linked complexes are formed in the presence of the Y141C mutation. Pictorial representation of velocity sedimentation data from Figure 7. RDS: black, ROM-1: white, Y141C-RDS: grey. Striped molecules could be either WT ROM-1 or Y141C-RDS (white and grey) or WT RDS or ROM-1 (black and white). Complexes that appear abnormal by non-reducing SDS–PAGE are underlined.
