Table 2.
Meta-analysis results for PC1
| SNP | Allele 1 | Allele 2 | Z-score | P-value | direction | Chr | Position | Gene | Feature | Left gene | Right gene |
|---|---|---|---|---|---|---|---|---|---|---|---|
| rs589636 | t | c | −5.40 | 6.61E-08 | ?------? | 13 | 76414577 | IRG1 | intron | BTF3L1 | LOC390413 |
| rs588702 | t | c | −5.33 | 9.75E-08 | ?------- | 13 | 76420926 | IRG1 | intron | BTF3L1 | LOC390413 |
| rs2687481 | t | g | −5.32 | 1.07E-07 | -------? | 7 | 125656358 | NA | NA | LOC646837 | GRM8 |
| rs2521030 | c | g | −5.23 | 1.69E-07 | -------? | 7 | 125656552 | NA | NA | LOC646837 | GRM8 |
| rs614171 | a | g | −5.23 | 1.71E-07 | ?------- | 13 | 76414753 | IRG1 | intron | BTF3L1 | LOC390413 |
Five SNPs were suggestive genome-wide significant (P < 5 × 10−7) associated with PC1. Meta-analysis results for PC1 are further characterized by non-effect allele (allele 1) and effect allele (allele 2), the resulting Z-score and significance of association (P-value). The direction of effect (minus or plus) is indicated for each of the eight included populations. If an SNP did not pass QC criteria for a certain SNP, this is indicated by a question mark (?) in the direction column. Mapping information for each SNP is specified by chromosome (chr), base-pair position (position), genes at this locus (gene) and surrounding the locus (left and right gene) as well as feature of the SNP position within a gene (feature).