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Characteristics of the synthesized glycoconjugates.
| Glyco conjugate | Activated ester/protein (mol/mol)a | Saccharide conjugation (mol/mol)b | MW (Da) | Loading efficiency %a |
| 14 | 75:1 | 7 | 61523 | 9 |
| 15 | 75:1 | 4.5 | 61731 | 6 |
| 16 | 75:1 | 4.7 | 63256 | 6 |
| MenXDP15CRM197 17 | 13:1 | 2.5 | n.d. | 19 |
aMol of activated glycan: mol of protein used in the conjugation reaction. bSugar:protein molar ratio determined by MALDI–TOF MS for 14–16, and by HPAEC-PAD analysis for MenXDP15-CRM197 conjugate 17.
