Table 4.
The epoxide ring opening reactions of 6a,b.
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| Entry | Epoxide | Nu | Catalyst | Product | Yield (%)a |
| 1 | 6a | 7d | Cs2CO3 | 13a | 68b |
| 2 | 6b | 7d | Cs2CO3 | 13b | 55b |
| 3 | 6a | 7a | Zn(ClO4)2·6H2O | 14a | 84c |
| 4 | 6b | 7a | Zn(ClO4)2·6H2O | 14b | 80c |
| 15 | 6d | ||||
aIsolated yield. bReagents and conditions: 5.0 mmol epoxide, 10.0 mol % catalyst, 6.5 mmol nucleophile, DMSO (10 mL), 120 °C, 2 h. cReagents and conditions: 5.0 mmol epoxide, 10.0 mol % catalyst, 6.5 mmol nucleophile, neat, 100 °C, 2 h. dRegioisomeric ratio (14b:15) – 12:1.
