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Numbers of significant HYPs at different richness and concordance thresholds in randomized data sets. Boxplot showing the number of HYPs (mechanisms) meeting the specified richness and concordance threshold across 1,000 randomized data sets. The number of significant HYPs at each threshold for the matching real data is plotted for comparison in green. (A) High Fat Diet, (B) TNF treatment, (C) PI3K inhibitor.
