Table 4.
Top 20 significant HYPs for TNF data set (GSE2638)
| Mechanism | Direction | Correct | Richness | Concordance | Ambiguous | Contra | Possible | Observed |
|---|---|---|---|---|---|---|---|---|
| tscript(complex(NCH:“Nfkb Complex”)) |
1 |
69 |
6.2E-25 |
9.2E-16 |
2 |
5 |
417 |
76 |
| path(SDIS:“bacterial infection”) |
1 |
34 |
1.6E-10 |
1.0E-09 |
0 |
1 |
211 |
35 |
| bp(GO:“replicative cell aging”) |
1 |
33 |
3.1E-19 |
1.1E-07 |
0 |
3 |
121 |
36 |
| p(PFH:“IFNA Family”) |
1 |
25 |
4.0E-12 |
4.0E-07 |
0 |
1 |
105 |
26 |
| a(CHEBI:lipopolysaccharide) |
1 |
26 |
1.8E-06 |
7.6E-06 |
0 |
3 |
225 |
29 |
| tscript(complex(NCH:“AP-1 Complex”)) |
1 |
19 |
2.1E-04 |
2.0E-05 |
0 |
1 |
167 |
20 |
| path(SDIS:“tissue damage”) |
1 |
19 |
1.2E-03 |
2.0E-05 |
0 |
1 |
191 |
20 |
| a(SCHEM:“Dietary Lipid”) |
1 |
14 |
1.0E-07 |
6.1E-05 |
0 |
0 |
51 |
14 |
| a(SCHEM:Allergens) |
1 |
17 |
4.5E-08 |
7.2E-05 |
0 |
1 |
80 |
18 |
| bp(GO:angiogenesis) |
1 |
20 |
6.7E-09 |
2.4E-04 |
0 |
3 |
115 |
23 |
| p(HGNC:AGT) |
1 |
17 |
4.0E-06 |
3.6E-04 |
0 |
2 |
117 |
19 |
| tscript(p(HGNC:TP63)) |
1 |
17 |
1.2E-05 |
3.6E-04 |
0 |
2 |
126 |
19 |
| kin(p(PFH:“PRKC Family”)) |
1 |
17 |
4.2E-04 |
3.6E-04 |
0 |
2 |
163 |
19 |
| kin(p(PFH:“MAPK p38 Family”)) |
1 |
14 |
6.8E-09 |
4.9E-04 |
0 |
1 |
49 |
15 |
| a(SCHEM:“Tetradecanoylphorbol acetate”) |
1 |
16 |
2.5E-04 |
6.6E-04 |
0 |
2 |
144 |
18 |
| bp(GO:“response to hypoxia”) |
1 |
49 |
7.8E-05 |
9.1E-04 |
1 |
22 |
943 |
72 |
| path(SDIS:“Photo-oxidative Stress”) |
1 |
10 |
3.6E-06 |
9.8E-04 |
0 |
0 |
34 |
10 |
| a(CHEBI:“arachidonic acid”) |
1 |
15 |
2.6E-07 |
1.2E-03 |
0 |
2 |
80 |
17 |
| tscript(p(HGNC:MEOX2)) |
−1 |
17 |
8.6E-10 |
1.3E-03 |
0 |
3 |
79 |
20 |
| a(SCHEM:“Oxidized Low Density Lipoprotein”) | 1 | 17 | 1.3E-04 | 1.3E-03 | 0 | 3 | 161 | 20 |
Fifty-eight HYPs met richness and concordance thresholds of p < = 0.1 for data set GSE2638; the top twenty significant HYPs, as ranked by concordance are shown.