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. 2013 Nov 21;13:258. doi: 10.1186/1471-2148-13-258

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Copyright © 2013 Deakin et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Derivation of (A) marsupial and (B,C) eutherian ancestral karyotypes from the predicted ancestral therian karyotype. (A) The predicted ancestral marsupial karyotype was formed by fusions of the predicted therian chromosomes. (B) Inversions, fusions and fissions led to (C) the previously predicted ancestral eutherian karyotype [40]. T – Therian, M- Marsupial. Chromosomes have been colour-coded to reflect homology with human chromosomes (refer to key in Figure 6).