Table 2.
Resistance mutations to | Gene | Mutations |
---|---|---|
Protease inhibitor (PI) |
Protease |
L10R, M46I, L63P, V82T, I84V |
Nucleoside RT inhibitor (NRTI) |
RT |
M41L, D67N, T69N, K70R, T215F, K219E |
Non-nucleoside RT inhibitor (NNRTI) |
RT |
K103N, Y181C |
Nucleoside and non-nucleoside RT inhibitor (Multi-drug) |
RT |
M41L, D67N, K103N, M184V, L210W, T215Y |
Integrase strand transfer inhibitor (INSTI) | Integrase | G140S, Q148H |
Mutant viruses used in this study that are resistant to PIs, NRTIs, Multi-drugs (NRTI + NNRTI), NNRTIs or INSTIs.