Figure 5. Schematic insertional translocation representation by non-allelic homologous recombination.

Purple: PAR1 reference sequence, red: unique X sequence, blue: unique Y sequence; yellow: LTR6B; At the top a paternal set of gonosomes: one normal X and one normal Y chromosome are shown, followed by non-allelic homologous alignment and crossover, resulting in an X chromosome containing a deletion and a Y chromosome containing an X insertion. The bottom illustration demonstrates the situation for male carriers with a Y chromosome containing an X insertion and the reciprocal deletion female carriers with an X chromosome containing a deletion.