Figure 3.

Core fucosylation in pooled samples of healthy controls (H), cirrhosis (CIR), and HCC patients. Core fucosylation of (A) hemopexin and (B) CFH was analyzed following endoglycosidase F2/F3 treatment. Relative abundance of each fucosylated glycoform, quantified as area of precursor ion XIC peak, is presented as a percent of its nonfucosylated counterpart. The position of the glycosylation site in the protein sequence is shown below the corresponding group of bars representing three patient groups. Results are shown as mean ± SD; ∗, P < 0.05 vs H; ND, nondetectable.