Table 1.
Baseline characteristics of the study populations
| DM (n=8) | Non-DM (n=13) | P value* | |
|---|---|---|---|
| Characteristics |
|
|
|
| Age (y) |
63.0 (57.2, 68.5) |
64.0 (45.5, 74.5) |
0.913 |
| Height (cm) |
166.8 (160.0, 171.3) |
167.0 (156.6, 169.4) |
0.772 |
| Dry weight (kg) |
68.4 (58.4, 81.1) |
57.0 (53.8, 65.0) |
0.051 |
| Female sex |
2(25.0) |
3 (23.1) |
0.920 |
| Smoking |
1(12.5) |
2 (15.4) |
0.854 |
| Drugs |
|
|
|
| Antihypertensives |
7(87.5) |
13 (100) |
0.192 |
| Antiplatelets |
5(62.5) |
5 (38.5) |
0.284 |
| Anticoagulants |
1(12.5) |
3 (23.1) |
0.549 |
| Statins |
3(37.5) |
3 (23.1) |
0.477 |
| Biochemical data |
|
|
|
| TP (g/dL) |
6.9 (6.7, 7.3) |
6.5 (6.1, 6.9) |
0.064 |
| Alb (g/dL) |
4.2 (3.8, 4.3) |
4.0 (3.7,4.4) |
0.689 |
| AST (IU/L) |
9.5 (9.0, 20.0) |
11.0 (6.5, 14.0) |
0.445 |
| ALT (IU/L) |
12.0 (9.3, 17.5) |
9.0 (8.0, 12.5) |
0.094 |
| LDH (IU/L) |
193.5 (182.8, 213.5) |
171.0 (148.5, 194.5) |
0.076 |
| ALP (IU/L) |
318.0 (193.8, 348.8) |
168.0 (157.5, 241.5) |
0.039 |
| BUN (mg/dL) |
61.0 (56.3, 72.3) |
60.0 (50.5, 68.5) |
0.405 |
| Cr (mg/dL) |
11.8 (9.7, 13.4) |
12.2 (10.2, 13.8) |
0.799 |
| UA (mg/dL) |
7.6 (5.4, 8.9) |
7.6 (6.5, 8.0) |
0.744 |
| β2-MG (mg/L) |
21.7 (18.2, 22.9) |
21.0 (20.0, 24.5) |
0.799 |
| NT-proBNP (pg/mL) |
3323 (1473, 6494) |
2657 (826, 12645) |
0.638 |
| Ca (mg/dL) |
8.8 (8.5, 9.6) |
9.1 (8.9, 9.5) |
0.611 |
| P (mg/dL) |
5.9 (5.0, 6.9) |
5.4 (4.9, 6.2) |
0.537 |
| iPTH (pg/mL) |
152.5 (70.8, 259.8) |
174.0 (82.0, 223.0) |
0.914 |
| Fe (μg/dL) |
64.5 (55.5, 82.8) |
73.0 (50.0, 94.0) |
0.612 |
| Ferritin (μg/L) |
74.5 (30.3, 241.8) |
245.0 (131.0, 393.5) |
0.120 |
| hs-CRP (mg/dL) |
0.10 (0.06, 0.31) |
0.06 (0.03, 0.13) |
0.403 |
| TG (mg/dL) |
129.0 (91.3, 190.0) |
100.0 (77.0, 141.0) |
0.277 |
| TC (mg/dL) |
152.0 (123.3, 184.0) |
163.0 (145.5, 201.0) |
0.246 |
| LDL-C (mg/dL) |
79.5 (54.5, 94.0) |
93.0 (72.5, 123.5) |
0.246 |
| HDL-C (mg/dL) |
39.0 (27.5, 54.5) |
42.0 (39.0, 51.5) |
0.663 |
| BS (mg/dL) |
148.0 (98.3, 195.5) |
107.0 (96.5, 116.5) |
0.180 |
| HbA1c (%) |
7.0 (6.6, 7.9) |
5.2 (4.8, 5.3) |
0.0002 |
| Hematologic data |
|
|
|
| WBC (103/μL) |
5.55 (4.90, 6.25) |
5.10 (4.15, 5.85) |
0.310 |
| Hb (g/dL) |
11.8 (11.0, 12.6) |
11.0 (10.5, 12.1) |
0.232 |
| Ht (%) |
37.0 (34.0, 38.9) |
34.1 (33.2, 36.2) |
0.168 |
| PLt (104/μL) |
19.1 (17.4, 23.6) |
15.0 (10.6, 17.9) |
0.020 |
| Dialysis parameters |
|
|
|
| HD duaration (y) |
5.2 (2.4, 6.3) |
4.1 (1.1, 13.7) |
0.971 |
| Kt/Vurea | 1.32 (1.25, 1.42) | 1.31 (1.21, 1.45) | 0.968 |
Data are presented in number (%) or median (interquartile range).
*p-values were calculated by Mann-Whitney test for continuous variables or Fishers exact test for categorical variables.
Abbreviations: DM diabetes mellitus, TP total protein, Alb albumin, AST aspartate aminotransferase, LDH lactase dehydrogenase, ALP alkaline phosphatase, BUN blood urea nitrogen, Cr reatinine, UA urinary acid, β2-MG beta2-microglobulin, NT-proBNP N-terminal pro-brain natriuretic peptide, Ca calcium, P phosphorus, iPTH intact parathyroid hormone, Fe ferrum, hsCRP high-sensitivity C-reactive protein, TG triglyceride, TC total cholesterol, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, BS blood sugar, HbA1c hemoglogin A1c, WBC white blodd cell, Hb hemoglobin, Ht hematocrit, PLt platelet, HD hemodialysis, Kt/Vurea Kt/V for urea.