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. Author manuscript; available in PMC: 2014 Nov 6.
Published in final edited form as: Eur J Immunol. 2006 Jul;36(7):1694–1706. doi: 10.1002/eji.200635897

Figure 2.

Figure 2

Bim levels are not increased in LCMV-specific T cells at the peak of the response. The top panels show a representative histogram of Bim staining intensity in CD4+ (upper left panel) and CD8+ (upper right panel) from either Bim+/+ (dark lines) or Bim−/− (dashed lines) mice. As a control, cells from Bim−/− mice were stained with an isotype control antibody (light lines). To assess Bim levels after infection, spleen cells from day 9 LCMV-infected Bim+/+ mice (n=3) were stained with MHC tetramers and intracellularly for Bim. Histograms are from representative animals and show the Bim staining intensity of MHC-tetramer-gated events. The mean fluorescence intensity (MFI) of anti-Bim staining on Dbnp396+; Dbgp33+; or I-Abgp61+ T cells is shown in the upper right corner. This experiment is one of two independent experiments with similar results.