Table 2.
Hematological parameters measured in BALB/c mice treated with different doses of EEGE for 35 days
|
Parameter (unit) |
Control |
EEGE 100 mg/kg |
EEGE 200 mg/kg |
EEGE 300 mg/kg |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean ± S.D. | Min | Max | Mean ± S.D. | Min | Max | Mean ± S.D. | Min | Max | Mean ± S.D. | Min | Max | |
| RBC (106/μl) |
9.44 ± 0.987 |
8.65 |
11.83 |
9.36 ± 1.58 |
7.68 |
12.0 |
8.76 ± 1.12 |
7.28 |
10.5 |
8.90 ± 1.05 |
8.12 |
10.8 |
| WBC (103/μl) |
5.12 ± 1.56 |
4.1 |
6.3 |
6.21 ± 1.48 |
4.87 |
7.23 |
5.18 ± 1.18 |
4.78 |
6.68 |
4.98 ± 1.47 |
4.2 |
6.85 |
| Lymphocytes (%) |
79.1 ± 6.34 |
74.3 |
88.4 |
83.2 ± 6.68 |
77.8 |
90.5 |
83.4 ± 11.2 |
74.9 |
85.3 |
79.9 ± 6.37 |
71.3 |
83.8 |
| Monocytes (%) |
6.4 ± 1.3 |
5.2 |
7.8 |
5.3 ± 1.8 |
3.52 |
6.81 |
5.80 ± 1.67 |
4.0 |
8.2 |
5.3 ± 1.8 |
4.2 |
7.5 |
| Eosinophils (%) |
1.2 ± 1.1 |
0 |
3.2 |
0.6 ± 0.3 |
0 |
1.1 |
1.4 ± 0.7 |
0 |
2.4 |
1.5 ± 0.70 |
0.1 |
2.2 |
| Basophils (%) |
0.8 ± 0.2 |
0 |
1.4 |
0.4 ± 0.3 |
0 |
1.2 |
00.9 ± 0.5 |
0 |
1.3 |
0.3 ± 0.15 |
0 |
1.1 |
| Platelet (105/μl) |
5.64 ± 1.78 |
3.25 |
8.21 |
7.12 ± 2.45 |
4.13 |
10.9 |
6.12 ± 1.98 |
3.48 |
9.25 |
6.45 ± 2.78 |
3.75 |
10.2 |
| HGB (g/dl) |
13.9 ± 1.58 |
12.4 |
17.1 |
13.4 ± 1.31 |
11.9 |
14.9 |
13.8 ± 1.48 |
12.1 |
14.8 |
13.2 ± 1.45 |
12.2 |
14.5 |
| HCT (%) |
40.8 ± 3.56 |
34.8 |
46.1 |
39.1 ± 5.11 |
34.1 |
47.2 |
42.1 ± 3.78 |
35.6 |
45.8 |
40.9 ± 4.32 |
36.2 |
43.2 |
| MCV (fl) |
52.4 ± 2.32 |
46.21 |
54.2 |
48.5 ± 2.36 |
44.5 |
51.2 |
51.3 ± 1.56 |
46.2 |
53.8 |
48.3 ± 1.23 |
44.8 |
51.6 |
| MCH (pg) |
16.2 ± 1.26 |
15.2 |
17.4 |
17.3 ± 1.49 |
14.3 |
18.5 |
16.4 ± 1.44 |
15.4 |
17.4 |
16.4 ± 1.29 |
15.4 |
17.9 |
| MCHC (g/dl) |
33.8 ± 3.44 |
30.4 |
36.1 |
32.8 ± 3.49 |
30.7 |
35.9 |
35.8 ± 2.45 |
31.5 |
37.9 |
33.1 ± 2.78 |
29.4 |
36.1 |
| PMN (%) | 15.6 ± 6.79 | 15.3 | 21.35 | 17.5 ± 5.89 | 15.56 | 22.1 | 17.1 ± 5.81 | 14.56 | 21.2 | 15.8 ± 6.10 | 13.62 | 18.99 |