Table 1. Summary of the genomic features of the Treponema pallidum subsp. endemicum Bosnia A strain and four T. pallidum subsp. pertenue strains (Samoa D, CDC-2, Gauthier and Fribourg-Blanc).
Genome parameter | Bosnia A | Fribourg-Blanca | Samoa Db | CDC-2b | Gauthierb |
GenBank accession number | CP007548.1 | CP003902.1 | CP002374.1 | CP002375.1 | CP002376.1 |
Genome size (bp) | 1,137,653 | 1,140,481 | 1,139,330 | 1,139,744 | 1,139,417 |
G+C content (%) | 52.77 | 52.80 | 52.80 | 52.80 | 52.80 |
Intergenic region length (bp) (% of the genome length) | 52,643 (4.63) | 52,785 (4.63) | 52,844 (4.64) | 52,963 (4.65) | 53,300 (4.68) |
Average/median gene length (bp) | 979.2/831.0 | 982.6/831.0 | 980.3/831.0 | 980.4/831.0 | 979.3/831.0 |
No. of predicted protein-encoding genes | 1063 | 1065 | 106810681068 | ||
No. of genes encoded on plus/minus DNA strand | 600/525 | 599/523 | 600/525600/525600/525 | ||
No. of genes coding for proteins with predicted function | 640 | 640 | 640640640 | ||
No. of genes coding for treponemal conserved hypothetical proteins | 137 | 139 | 140140140 | ||
No. of genes coding for conserved hypothetical proteins | 141 | 141 | 141141141 | ||
No. of genes coding for hypothetical proteins | 145 | 145 | 147147147 | ||
No. of annotated pseudogenes (no. of pseudogenes when compared to the Nichols CP004010.2 genome sequencec) | 8 (16) | 3 (14) | 3 (12)3 (12)3 (12) | ||
No. of tRNA loci | 45 | 45 | 454545 | ||
No. of rRNA loci | 6 (2 operons) | 6 (2 operons) | 6 (2 operons)6 (2 operons)6 (2 operons) | ||
No. of ncRNAs | 3 | 3 | 333 |