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A, Infected macrophage adhesion is downregulated in the vaccine line (V-Delta 169) compared to virulent (V) Jed 4. RT-qPCR determined levels of genes (cd69, icam-1, cd49 and itgb5) potentially involved in mediating adhesion. B, Virulent Jed 4 binds at high density to fibronectin compared to the V-Delta 169 vaccine line; 70% of fibronectin binding capacity is lost upon ablation of c-Jun.
