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. 2014 Nov 6;9(11):e111453. doi: 10.1371/journal.pone.0111453

Figure 2. Distribution of proliferating cells in a mouse brain.

Figure 2

A–C. Distribution of proliferating cells in the brain of a 60 day-old mouse (A), 120 day-old mouse (B), and 240 day-old mouse (C). Each EdU-labeled nucleus is shown as a black dot. D–F. Distribution of proliferating cells in the lateral walls of the lateral ventricles (LatW), the dentate gyrus of the hippocampus (DG) and the rostral migratory stream (RMS) of a 120 day-old mouse. Each EdU-labelled nucleus is shown as a yellow dot in the LatW, a green dot in the DG, and a lilac dot in the RMS. EdU-labelled nuclei outside of these three structures are shown as black dots of smaller size. D. All proliferating cells in the brain. E. Proliferating cells in the LatW, DG and RMS. F. Proliferating cells located outside the LatW, DG and RMS. The brain shape is outlined with a black line. Frontal, lateral, and dorsal views of the brain are shown. Mice are labeled with EdU for one hour.