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. 2014 Nov 6;9(11):e112076. doi: 10.1371/journal.pone.0112076

Figure 6. The effects of cAMP pathway mutants on retrogressions.

Figure 6

A. cAMP pathway mutants demonstrate a stronger aftereffect following the end of electric shock. Retrogression was measured over the first four steps following an electric shock of 30 seconds. n = 16–20. p = 0.0097, Kruskal-Wallis test. * p<0.05, Mann-Whitney test with bonferroni correction for multiple comparisons. B. cAMP pathway mutants demonstrate a stronger aftereffect following the end of combined amputation and 2 hour suspension. n = 20–26. p = 0.0037, Kruskal-Wallis test. * p<0.05 ** p<0.01 Mann-Whitney test with bonferroni correction of p values. C. cAMP pathway mutants accumulate stress more rapidly than wild type flies. In order to compare the kinetics of stress induction between mutants, retrogression was determined immediately following different suspension times, and normalized to the retrogression levels after a 2 hour hanging period for each group. n≥8. Error bars are mean ±SEM.