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. Author manuscript; available in PMC: 2015 Apr 8.
Published in final edited form as: Toxicol Pathol. 2014 Feb 4;42(4):672–683. doi: 10.1177/0192623313518664

Figure 6.

Figure 6

von Willebrand Factor (VWF) immunohistochemistry staining of canine coronary artery 24 hr after treatment with the PCO ZD6169. Dogs were euthanatized 24 hr after bolus treatment with 60 mg/kg ZD6169. Heart was processed, fixed, sectioned, and immunohistochemically stained for VWF. Note: VWF within the smooth muscle layer (@) of the vascular wall. * is showing endothelial cells expressing VWF.