Figure 6.
von Willebrand Factor (VWF) immunohistochemistry staining of canine coronary artery 24 hr after treatment with the PCO ZD6169. Dogs were euthanatized 24 hr after bolus treatment with 60 mg/kg ZD6169. Heart was processed, fixed, sectioned, and immunohistochemically stained for VWF. Note: VWF within the smooth muscle layer (@) of the vascular wall. * is showing endothelial cells expressing VWF.