EPO stimulated antioxidant protein expression in brain microvascular endothelial cells. Representative Western blots and densitometric analysis from GTPCH-I siRNA treated BMECs exposed to EPO demonstrated significant increase in expression of MnSOD (A), while expression of CuZnSOD (B) remained unchanged (*P<0.05, ** P<0.01, n=6). Furthermore, EPO treatment also increased expression of catalase (C, * P<0.05, n=6).