. Author manuscript; available in PMC: 2016 Jan 1.

Published in final edited form as: Contrast Media Mol Imaging. 2014 May 6;10(1):51–58. doi: 10.1002/cmmi.1604

Table 1.

BIRDS characterization of ¹H resonances in Tm-DOTA-4AmP^5- and Yb-DOTA-4AmP^5-

	Tm-DOTA-4AmP^5-		Yb-DOTA-4AmP^5-
Resonance	pH sensitivity (ppm/pH unit)^a	Temperature sensitivity (ppm/°C)^b	pH sensitivity (ppm/pH unit)^a	Temperature sensitivity (ppm/°C)^b
H4	−3.9 ± 0.3	−1.49 ± 0.03	−0.62 ± 0.04	−0.52 ± 0.01
H2	−0.63 ± 0.04	−0.24 ± 0.01	−0.07 ± 0.01	−0.079 ± 0.001
H3	−0.25 ± 0.03	−0.188 ± 0.004	0.03 ± 0.01	−0.063 ± 0.001
H7	0.24 ± 0.04	0.121 ± 0.002	0.001 ± 0.001	0.051 ± 0.001
H8	−4.0 ± 0.2	0.170 ± 0.003	−1.68 ± 0.03	0.069 ± 0.001
H6	1.2 ± 0.1	0.47 ± 0.01	0.20 ± 0.02	0.17 ± 0.002
H1	1.8 ± 0.1	0.54 ± 0.01	0.38 ± 0.03	0.199 ± 0.002
H5	1.0 ± 0.1	1.04 ± 0.02	−0.27 ± 0.03	0.373 ± 0.004
H3-H2	0.37 ± 0.02	0.054 ± 0.001	-	-
H6-H8	5.2 ± 0.2	0.30 ± 0.01	-	-
H1-H8	-	-	2.1 ± 0.1	0.130 ± 0.002
H5-H4	-	-	0.35 ± 0.05	0.89 ± 0.01

Measured at 35 °C.

Measured at pH 7.50.

^c Measured at pH 7.48.