Table 1. Susceptibility of GP and rabbits to Vollum strains in the IC injection model.
| Guinea Pigs | ||||
| Strain | Description | Inoculum (CFU) | Dead/infected | TTD (days) |
| Vollum | pXO1+pXO2+ | 105 | 4/4 | 1 |
| Vollum ΔpXO1 | pXO1−pXO2+ | 105–103 | 4/4 | 1 |
| Vollum ΔpXO2 | pXO1+pXO2− | 105 | 4/4 | 1 |
| VollumΔpagΔlefΔcya | Complete deletion of the pag, lef and cya genes | 105–103 | 4/4 | 1 |
| Vollum ΔpXO2 ΔpagΔlefΔcya | Complete deletion of pXO2 and the pag, lef and cya genes | 105 | 0/4 | >14 |
| Vollum ΔpXO1 ΔpXO2 | pXO1−pXO2− | 105 | 0/4 | >14 |
| Rabbits | ||||
| Strain | Characterization | Inoculum (CFU) | Dead/infected | TTD (days) |
| Vollum | pXO1+pXO2+ | 105 | 4/4 | 1 |
| Vollum ΔpXO1 | pXO1−pXO2+ | 105 | 4/4 | 1 |
| Vollum ΔpXO2 | pXO1+pXO2− | 105 | 5/6 | 1–6 |
| VollumΔpagΔlefΔcya | Complete deletion of the pag, lef and cya genes | 105 | 4/4 | 1–2 |
| Vollum ΔpXO2 ΔpagΔlefΔcya | Complete deletion of pXO2 and the pag, lef and cya genes | 105 | 0/4 | >14 |
| Vollum ΔpXO1 ΔpXO2 | pXO1−pXO2− | 105 | 0/4 | >14 |