Table 1. The association of DACT2 methylation and clinical factors in 99 cases of papillary thyroid cancer.
DACT2 methylation status | ||||
Clinical Factor | No. | methylated | unmethylated | p value |
n = 64(64.6%) | n = 35(35.4%) | (χ2 test) | ||
Age(years) | ||||
<46 | 56 | 39 | 17 | 0.235 |
≥46 | 43 | 25 | 18 | |
Gender | ||||
Male | 28 | 17 | 11 | 0.607 |
Female | 71 | 47 | 24 | |
Tumor Size(cm) | ||||
≤1 | 33 | 21 | 12 | 0.882 |
>1 | 66 | 43 | 23 | |
Lymph Node Metastasis | ||||
Negative | 50 | 25 | 25 | 0.002** |
Positive | 49 | 39 | 10 |
DACT2 methylation is associated with lymph node metastasis of papillary thyroid cancer (p = 0.002).
**p values are obtained from x2 test, significant difference, p<0.01.