Table 4. Diagnostic accuracy determined by computing the AUROCs, best sensitivity-specificity balance, likelihood ratios, and sensitivity at the fixed specificities for the optic nerve head parameters of OCT and HRT to discriminate between CON eyes with a glaucoma-like disc and glaucoma eyes.

OCT and HRT parameters	AUROC	95% CI	AUROCs P Value	Cutoff Point	Sensitivity (%)	Specificity (%)	+LR	−LR	Sensitivity
									Specificity 90%	Specificity 95%
BMO-anterior LC	0.754	0.610–0.866	0.0009	395 µm	73.33	79.41	3.56	0.34	33.33	13.33
Mean cupping depth	0.803	0.662–0.903	<0.0001	0.27 mm	85.71	67.65	2.65	0.21	41.43	14.29
Maximum cupping depth	0.829	0.692–0.922	<0.0001	0.6 mm	85.71	73.53	3.24	0.19	57.14	28.57

AUROC =  area under the receiver operating characteristic curve; OCT =  optical coherence tomography; HRT  =  Heidelberg Retina Tomography; CI =  confidence interval; +LR =  positive likelihood ratio; −LR =  negative likelihood ratio; BMO-anterior LC =  distance between Bruch's membrane opening and anterior surface of lamina cribrosa.

Note: The cutoff points were calculated using the MedCalc software as the points with the best sensitivity-specificity balance. Sensitivities at fixed specificities of 90% and 95% are shown.