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. 2014 Oct 15;16(5):458. doi: 10.1186/s13075-014-0458-4

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© Finckh et al.; licensee BioMed Central Ltd. 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Flow diagram of the study. Displays the study flow: 49 patients were screened, 26 corresponded to the inclusion and exclusion criteria and signed the study informed consent form, 21 (81%) finished the first treatment period and 20 (95%) the second treatment period. Overall, 25 patients completed the methotrexate (MTX) treatment period and 21 the placebo (PBO) treatment period.