Table 1.
Probiotics | Author's conclusions | Ref. |
Treating acute infectious diarrhea | Beneficial effects | [109] |
Prevention of pediatric antibiotic associated diarrhea | Evidence of a protective effect | [110] |
Treating persistent diarrhea in children | Limited evidence | [111] |
Treatment of Clostridium difficile (C. difficile)-associated colitis in adults | Insufficient evidence | [112] |
Prevention of C. difficile-associated diarrhea in adults and children | Moderate quality evidence | [113] |
Prevention of necrotizing enterocolitis in preterm infants | Prevents severe necrotizing enterocolitis | [114] |
Induction of remission in ulcerative colitis | Limited evidence | [115] |
Treatment and prevention of pouchitis after ileal pouch-anal anastomosis for chronic ulcerative colitis | Probiotic VSL#3 was more effective than placebo | [116] |
Maintenance of remission in ulcerative colitis | Insufficient evidence | [117] |
Maintenance of remission in Crohn's disease | No evidence | [118] |
Induction of remission in Crohn's disease | Insufficient evidence | [119] |
Prevention of post-operative recurrence of Crohn's disease | Insufficient randomized trials | [120] |
Non-alcoholic fatty liver disease and/or steatohepatitis | Lack of randomized clinical trials | [121] |
Patients with hepatic encephalopathy | Need of efficacy demonstration | [122] |
Treatment of bacterial vaginosis | No sufficient evidence | [123] |
Preventing preterm labour | Insufficient data | [124] |
For prevention of allergic disease and food hypersensitivity (in infants) | Insufficient evidence | [125] |
Treating eczema | No effective treatment | [126] |
Preventing acute upper respiratory tract infections | Limited evidence | [127] |
Reviews obtained from the search into “probiotics” in the Cochrane Library (http://onlinelibrary.wiley.com/cochranelibrary/search) of the Cochrane Database of Systematic Reviews journal.