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. 2014 Sep 18;289(45):31341–31348. doi: 10.1074/jbc.M114.605451

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© 2014 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 4. — Structure of the polβ:Pt-GG·dCTP*-Mn²⁺ ternary complex (Protein Data Bank code 4TUS). A, overall structure of the Pt-GG·dCTP*-Mn²⁺ ternary complex. B, overlay of the Pt-GG·dCTP*-Mg²⁺ (white) and the Pt-GG·dCTP*-Mn²⁺ (cyan) structures. C, close-up view of the active site region of the Pt-GG·dCTP*-Mn²⁺ structure. D, overlay of the active site region of the Pt-GG·dCTP*-Mg²⁺ (white) and the Pt-GG·dCTP*-Mn²⁺ (multicolored) structures. E, comparison of the unmodified GG·dCTP*-Mg²⁺ (yellow) and the Pt-GG·dCTP*-Mn²⁺ (multicolored) structures.