FIGURE 3.

Effect of 2 μm curcumin in combination with 35 nm gA or with 7.5 nm ouabain on the accumulation of Bp in HEK-293 control and HEK-ABCG2 cells. HEK-293 control cells (A and B) and HEK-ABCG2 cells (C and D) were incubated in the absence (red curve) or presence of 250 nm Bp alone (peak 1) or in combination with 10 μm FTC (peak 2), 35 nm gA (peak 3), 2 μm curcumin (peak 4), a combination of 35 nm gA and 2 μm curcumin (peak 5), 7.5 nm ouabain (peak 6), and a combination of 7.5 nm ouabain and 2 μm curcumin (peak 7).