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. 2014 Sep 24;289(45):31397–31410. doi: 10.1074/jbc.M114.576819

FIGURE 8.

FIGURE 8.

Sensitivity of HEK-293 control and HEK-ABCG2 cells to inhibitors of the electron transport chain. A, toxicity of increasing concentrations of rotenone on HEK-ABCG2 (red) and parental cells (black) in the absence (solid curve) or presence of 2 μm curcumin and 35 nm gA (dashed curve). B, toxicity of increasing concentrations of rotenone on HEK-ABCG2 (red) and parental cells (black) in the absence (solid curve) or presence of 2 μm curcumin and 7.5 nm ouabain (dashed curve). C, toxicity of increasing concentrations of antimycin A on HEK-ABCG2 (red) and parental cells (black) in the absence (solid curve) or presence of 2 μm curcumin and 35 nm gA (dashed curve). D, toxicity of increasing concentrations of antimycin A on HEK-ABCG2 (red) and parental cells (black) in the absence (solid curve) or presence of 2 μm curcumin and 7.5 nm ouabain (dashed curve). The open symbols in C and D indicate that antimycin was not soluble at this concentration. These points were not included in the best curve fits.