Table 3.
Comparison of mRNA expression of MCM2, MCM3 and MCM7 in glioma tumor tissue by microarray analysis (Rembrandt,https://caintegrator.nci.nih.gov/rembrandt/)
|
Gene |
Unique ID |
Gene origin |
Number of samples (all upregulate) |
Fold |
p
value |
|
|---|---|---|---|---|---|---|
| Group 1 | Group 2 | Cut-off point | ||||
| MCM2 |
202107_s_at |
Microarray |
133 |
48 |
2.0 |
0.181 |
| MCM3 |
201555_at |
Microarray |
138 |
43 |
2.0 |
0.417 |
| MCM7 | 208795_s_at | Microarray | 59 | 122 | 3.0 | 0.009 |
p < 0.05.
MCM2 and MCM3 were not correlate with the prognosis of GBM patients (p > 0.05). When the cutoff point was the up-regulation of 3fold, MCM7 was significant correlate with the outcome of GBM patients (p < 0.01).