Table 1.
Trait | Module | Genes in the Module | Gene Expression Sample | ESa | NESa | NOM P Valuea |
---|---|---|---|---|---|---|
FN | 1 | SP1, BCL6, ESR1, WNT16, ESRRA, MEF2C | Caucasian | – | – | – |
Chinese | −0.779 | −1.457 | .043 | |||
SPN | 2b | SMAD3, ESR1, DKK1, FN1, SFRP2, TNFRSF11B, SMAD9, LRP5, WNT1, SECISBP2, WNT4 | Caucasian | −0.583 | −1.500 | .049 |
Chinese | −0.621 | −1.722 | .024 | |||
Hip | 3b | MDFI, ESR1, TAP1, DKK1, LRP5, ZNF408, SFRP1, EXOSC2, WNT1, WNT4 | Caucasian | −0.685 | −1.618 | .023 |
Chinese | −0.657 | −1.577 | .021 |
Abbreviations: ES, enrichment score; NES, normalized enrichment score; NOM, nominal. Dashes, not significant.
Results in low-BMD group.
Final candidate module.