Table 4.
Cognitive measures
| Cognitive measures |
Placebo |
Olanzapine |
|||||
|---|---|---|---|---|---|---|---|
|
Baseline |
Day 2-4 |
Day 28-31 |
Baseline |
Day 2-4 |
Day 28-31 |
ANOVA |
|
| Mean ± SD | Mean ± SD | ||||||
| SWM |
|
|
|
|
|
|
|
| Between errors |
23 ± 26 |
22 ± 23 |
12 ± 15 |
34 ± 24 |
31 ± 19 |
21 ± 21 |
p = .778 |
| Strategy score |
29 ± 8.4 |
29 ± 7.6 |
28 ± 7.8 |
31 ± 8.0 |
30 ± 7.0 |
31 ± 6.9 |
p = .562 |
| RTI |
|
|
|
|
|
|
|
| Reaction time |
410 ± 80.6 |
395 ± 43.3 |
405 ± 52 |
410 ± 110 |
380 ± 92.8 |
388 ± 111 |
p = .333 |
| Movement time |
579 ± 110 |
567 ± 104 |
539 ± 61 |
542 ± 132 |
563 ± 136 |
530 ± 107 |
p = .395 |
| SSP | 5.8 ± 1.4 | 5.7 ± 1.6 | 5.6 ± 1.6 | 5.4 ± 1.4 | 5.4 ± 1.2 | 5.7 ± 1.4 | p = .296 |
The mean ± standard deviation (SD) of cognitive measures for both olanzapine and placebo treated group.SWM = Spatial Working Memory task, RTI = Reaction Time task, SSP = Spatial Span task. P value reported for the interaction (time by treatment) of a two-way repeated measures ANOVA.