Table 1.
Clinicopathologic features of high-grade serous carcinoma with and without STICHGSC: high-grade serous carcinoma; STIC: serous tubal intraepithelial carcinoma
| |
HGSC w/ STIC (n = 48) |
HGSC w/o STIC (n = 62) |
P |
|---|---|---|---|
| No. (%) patients | |||
|
Age (y) mean ± SD |
57.2 ± 2.78 |
67.1 ± 2.32 |
< 0.005 |
| ≦40 |
4 |
2 |
|
| 41-50 |
9 |
6 |
|
| 51-60 |
18 |
11 |
|
| 61-70 |
10 |
22 |
|
| > 70 |
7 |
21 |
|
|
STIC locations |
|
|
|
| Left tube |
12 |
|
|
| Right tube |
29 |
|
|
| Bilateral tubes |
7 |
|
|
|
Invasive locations^ |
|
|
|
| Left |
3 |
4 |
|
| Right |
5 |
6 |
|
| Bilateral |
37 |
52 |
> 0.05 |
|
Cancer size (cm) mean ± SD |
|
|
|
| Fallopian tube |
0.55 ± 0.21 |
2.66 ± 0.72 |
< 0.05 |
| Ovary |
3.42 ± 0.52 |
4.35 ± 0.64 |
> 0.05 |
|
Stage |
|
|
|
| I |
4 |
0 |
< 0.05 |
| II |
5 |
3 |
> 0.05 |
| III |
39 |
51 |
> 0.05 |
| IV |
0 |
8 |
< 0.05 |
|
Breast cancer history |
8 |
7 |
|
|
Family history |
12 |
12 |
|
| Prophylactic BSO | 5 | 0 | |
^indicating the adnexal location of those invasive cancers. Among the 48 STIC patients, 3 showed STIC only without invasive component. w/: with; w/o: without.
For those cases without gross lesions in the fallopian tube, the lesion size was measured microscopically.