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. 2014 Jul 22;15:622. doi: 10.1186/1471-2164-15-622

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Copyright © 2014 Backes et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Difference between row- and column permutations. The histograms in panel A and B show for two pathways the significance values as calculated for row and column permutations, respectively. Panels C and D present the respective pathways as provided by KEGG. Here, red marked genes correspond to significant genes in our GWAS.