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TERTpromoter mutations in SCC of urinary bladder cancer. Shown are representative sequence of the wild-type TERT promoter and TERT promoter mutation as indicated for bladder cancer. The upper portion of the figure shows the sense sequences of the wild-type DNA and the nucleotide changes of C228T mutation. The lower portion of the figure shows the antisense sequences of the wild-type DNA and the nucleotide changes of the G228A mutation.
