Table 2.
Meta-analysis for the outcomes of CRTS versus SA
| Outcomes | Included studies | Sample size | Analysis model | Test for overall effect | P value for heterogeneity | P value for Egger’s test | ||
|---|---|---|---|---|---|---|---|---|
| |
|
CRTS |
SA |
F |
RR (95% CI) |
P |
|
|
| Postoperative mortality |
7 |
492 |
545 |
F |
0.64 [0.49, 0.84] |
0.001 |
0.83 |
0.040 |
| Postoperative complication |
10 |
586 |
641 |
F |
1.09 [0.96, 1.24] |
0.18 |
0.75 |
0.752 |
| Local recurrence |
8 |
484 |
481 |
F |
0.51 [0.38, 0.70] |
<0.0001 |
0.32 |
0.386 |
| Postoperative metastasis | 8 | 484 | 481 | F | 0.82 [0.68, 0.98] | 0.03 | 0.25 | 0.016 |
CRTS: chemoradiotherapy followed by surgery SA: surgery alone.