Table 3.
Effect of portfolio and control diets on blood lipids levels and the differences between dietary interventions
Treatments a | Between treatment differences b | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Variable | Portfolio intensive (n = 101) | Portfolio routine (n = 122) | Control (n = 122) | PI vs. PR | PI vs. C | PR vs. C | ||||||
Wk 0 | Wk 24 | Wk 0 | Wk 24 | Wk 0 | Wk 24 | Mean (95% CI) | P-value | Mean (95% CI) | P-value | Mean (95% CI) | P-value | |
Cholesterol, mmol/L | ||||||||||||
Total | 6.53 | 5.88 | 6.63 | 6.04 | 6.46 | 6.41 | -0.07 (-0.31, 0.17) | 0.777 | -0.56 (-0.80, -0.33) | <0.0001 | -0.49 (-0.73, -0.26) | <0.0001 |
LDL-C | 4.42 | 3.80 | 4.50 | 3.92 | 4.35 | 4.24 | -0.06 (-0.27, 0.15) | 0.773 | -0.46 (-0.67, -0.26) | <0.0001 | -0.40 (-0.60, -0.20) | <0.0001 |
HDL-C | 1.42 | 1.39 | 1.40 | 1.39 | 1.39 | 1.40 | 0.007 (-0.006, 0.072) | 0.965 | -0.02 (-0.09, 0.04) | 0.619 | -0.03 (-0.09, 0.03) | 0.453 |
Triglycerides | 1.52 | 1.50 | 1.61 | 1.60 | 1.66 | 1.72 | -0.06 (-0.23, 0.12) | 0.743 | -0.10 (-0.27, 0.07) | 0.372 | -0.04 (-0.21, 0.13) | 0.824 |
Total:HDL-C | 4.81 | 4.44 | 5.01 | 4.60 | 4.93 | 4.87 | -0.05 (-0.27, 0.17) | 0.852 | -0.33 (-0.54, -0.11) | 0.001 | -0.28 (-0.50, -0.06) | 0.008 |
Apolipoproteins g/L | ||||||||||||
A1 | 1.60 | 1.60 | 1.60 | 1.60 | 1.60 | 1.59 | 0.02 (-0.02, 0.06) | 0.533 | 0.01 (-0.03, 0.05) | 0.868 | -0.01 (-0.05, 0.03) | 0.819 |
B | 1.23 | 1.10 | 1.26 | 1.14 | 1.20 | 1.20 | -0.01 (-0.06, 0.03) | 0.846 | -0.11 (-0.16, -0.07) | <0.0001 | -0.10 (-0.15, -0.06) | <0.0001 |
aFor paired samples T-test of change from baseline, done on absolute change values.
bUsing analysis of covariance with sex, treatment and sex by treatment interaction as main effects and baseline as a covariate. A Tukey adjustment was made for multiple comparisons. Abbreviations: PI Portfolio intensive, PR Portfolio routine, C Control.