Table 1.
Data collection and refinement statistics
| Crystal 1 CTNav1.5-CaM-Mg2+ |
Crystal 2 CTNav1.5-CaM- Mg2+ |
||
|---|---|---|---|
| Data collection | |||
| Space group | P21 | P21 | |
| Cell dimensions | |||
| a, b, c (Å) | 106.0, 98.4,109.2 | 106.1, 99.0, 109.2 | |
| α, β, γ (°) | 90.0, 106.4, 90.0 | 90.0, 106.1, 90.0 | |
| Wavelength (Å) | 0.9793 (IP) | 0.9537 (RM) | 0.97929 |
| Resolution (Å) | 50.0–3.2 (3.26–3.20) |
50.0–3.2 (3.26–3.20) |
50.0–2.8 (2.85–2.80) |
| Rsym | 0.12(0.87) | 0.13(0.89) | 0.11 (0.74) |
| I / σI | 15.57 (2.30) | 15.0 (2.10) | 32.8(1.90) |
| Completeness (%) | 99.9 (99.9) | 99.9 (99.9) | 90.3 (58.3) |
| Redundancy | 4.6(4.5) | 3.2(3.2) | 3.3 (2.3) |
| Refinement | |||
| Resolution (Å) | 50.0–2.8 | ||
| No. reflections | 311,500 | ||
| Rwork / Rfree | 21.6/28.6 | ||
| No. atoms | |||
| Protein | 11,710 | ||
| Ligand/ion | 66 | ||
| Water | 89 | ||
| B factors | |||
| Protein | 81.2 | ||
| Ligand/ion | |||
| Water | 95.0 | ||
| r.m.s. deviations | |||
| Bond lengths (Å) | 0.011 | ||
| Bond angles (°) | 1.8 | ||