Figure 4.

Cross-reactive carbohydrate determinants (CCD) inhibition as observed on multi-allergen test strips. Custom-made test strips with CCD markers were incubated with serum in the absence (n) or presence (i) of inhibitor (20 μg/ml). The boxes mark allergens that may exhibit CCD-based IgE binding. Sera A, B and C were obtained from patients f16, m19 and f12 (a CCD-negative patient). The * denotes a mechanical scratch in panel C. The results of CAP tests performed with serum B (insert B-CAP) show that CCD inhibition does not affect exclusively protein-based reactions with allergen components.