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. 2014 Aug 7;2:90. doi: 10.1186/s40478-014-0090-1

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© Doorn et al.; licensee BioMed Central Ltd. 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Quantification of TLR2 immunoreactivity (IR) in the substantia nigra (SN) of control subjects, iLBD cases and PD patients. A significant increase was found in TLR2 IR in the SN of iLBD cases compared to control subjects and PD patients (#p < 0.05 vs Ctr, PD). In PD patients, TLR2 IR was significantly increased in the SN compared to the SN of control subjects (*p = 0.0001 vs Ctr). Data represent mean ± SEM.