Table 3.

Drug group comparisons^a of intracranial volume and total brain segmented tissue volumes^b (mm³).

	Group F(4,118)	PCE Mean (SE)	CTL Mean (SE)	NCOC Mean (SE)	PCE vs CTL % difference	PCE vs NCOC % difference
ICV^a	ns	482,825 (6558)	481,227 (5909)	467,072 (6545)
GM^b	7.46, 0.0009	230, 978 (1,166)	237,079 (1,050)	235,651 (1,184)	−2.6 %^***	−2.0%^**
WM^b	ns	182,399 (859)	182,713 (716)	181,950 (704)
CSF^b	4.74, .0106	66,004 (1,411)	60,665 (1,176)	61,665(1,157)	+9%^**	+6.2^*

PCE: Prenatal Cocaine Exposure; CTL: Drug-free Control; NCOC: Non-Cocaine Drug Exposure; ICV: Intracranial volume, GM: Total gray matter, WM: Total white matter, CSF:Total cerebral spinal fluid;

Adjusted for scanner, gender, birth weight, age at MRI, maternal age;

Adjusted for ICV, scanner, gender, birth weight, age at MRI, maternal age.

p <.05,

^**

p <.01,

^***

p < .005,