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. 2014 Nov 1;17(11):1204–1213. doi: 10.1089/jmf.2014.0037

FIG. 8.

FIG. 8.

DAPP was tested for its ability to inhibit two enzymes involved in inflammatory processes: Cyclooxygenase-2 (COX-2) and lipoxygenase. The tests compared a crude water extract of DAPP to a<3 kDa DAPP LMW. The crude extract showed inhibition of both enzymes at a dose of 10 mg/mL. The<3 kDa LMW fraction provided a proportionally better inhibition of COX-2 than lipoxygenase when compared with the crude water extract, suggesting that compounds below 3 kDa are involved in the inhibition of COX-2.