FIG. 1.

Mild lateral fluid percussion injury (LFPI) effects on pattern and strength of multiunit cluster responses evoked by simple trapezoidal stimuli. Population peristimulus time histograms are shown in (A) in response to the trapezoid with the fastest ramp velocity (400 mm/sec) in the various lamina (indicated to the left of the panel). Recordings are from sham surgery animals and from locations contralateral (contra) and ipsilateral (ipsi) to the LFPI site. Each Grand peristimulus time histogram was generated by averaging responses across all responsive clusters within that lamina. The grey-shaded box represents the analysis window used to extract response metrics. (B) Peak firing rate extracted from the onset response to simple trapezoidal stimuli from clusters ipsilateral to the site of injury (white circles), contralateral to the site of injury (grey circles), and in sham animals (black circles). Data represent averages from all responsive clusters (±standard error of the mean) at all tested ramp velocities, separated by cortical lamina. Each row of data comes from the same lamina as designated by the labels on the left (*=ipsilateral vs. sham; p<0.05).