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. 2014 Dec 1;21(16):2208–2230. doi: 10.1089/ars.2014.5845

FIG. 2.

FIG. 2.

Hypoxia reduces synaptic markers protein levels in the aging APP/PS1 mice. (A) Representative Western blot images of synaptic markers, detected with anti-synaptophysin (SYP), anti-synapsin I, and anti-synaptosomal-associated protein 25-kDa (SNAP-25), and normalized to GAPDH in the brains of APP/PS1 transgenic (APP/PS1) mice and age-matched WT C57BL/6 mice. (B–D) Quantification indicates the levels of SYP, synapsin I, and SNAP-25 in the mice brain. **p<0.01 versus WT group, ##p<0.01 versus Tg group, and $$p<0.01 versus WT+Hypo group by two-way ANOVA, n=6–8 in each group. Values represent the mean±SEM.