Table 1.

Composition of different proliposomes used in the study

Proliposomes	Composition	Organic solvents
SCF-EPCS and Film-EPCS	Lipoid EPCS (200 mg) Cholesterol (100 mg) CsA (50 mg) Lactose (900 mg)	Ethanol (3 mL)
SCF-DSPG and Film-DSPG	HSPC (100 mg) DSPG, Na (50 mg) DSPC (50 mg) Cholesterol (100 mg) CsA (50 mg) Lactose (900 mg)	Methanol (2 mL) Chloroform (1 mL)

Abbreviations: SCF-EPCS and Film-EPCS, proliposomes containing Lipoid EPCS prepared by supercritical fluid of carbon dioxide and conventional film methods; SCF-DSPG and Film-DSPG, proliposomes containing HSPC, DSPC, DSPG prepared using supercritical fluid of carbon dioxide and conventional film methods; CsA, cyclosporin A; EPCS, phosphatidylcholine from egg lecithin; HSPC, hydrogenated soy phosphatidylcholine; DSPC, distearoylphosphatidylcholine; DSPG, Na, distearoylphosphatidylglycerol, sodium salt.