Table 2.
Proliposome | Mean diameter (nm) | PDI | Zeta potential (mV) |
---|---|---|---|
SCF-EPCS | 1,012±170 | 0.34±0.03 | −23.07±3.37 |
Film-EPCS | 2,591±400 | 0.60±0.10 | −19.43±2.98 |
SCF-DSPG | 866±194 | 0.34±0.05 | −31.64±2.06 |
Film-DSPG | 1,518±471 | 0.47±0.05 | −35.48±3.71 |
Note: Values denote the mean ± standard deviation of four separate sets of experiments.
Abbreviations: SCF-EPCS and Film-EPCS, proliposomes containing Lipoid EPCS prepared by the supercritical fluid of carbon dioxide and conventional film methods; SCF-DSPG and Film-DSPG, proliposomes containing HSPC, DSPC, DSPG prepared using supercritical fluid of carbon dioxide and conventional film methods; PDI, polydispersity index; HSPC, hydrogenated soy phosphatidylcholine; DSPC, distearoylphosphatidylcholine; DSPG, distearoylphosphatidylglycerol; EPCS, phosphatidylcholine from egg lecithin.